GC
Gas chromatography (GC) is a core analytical platform for volatile and semi-volatile compounds in pharmaceutical R&D and QC. This category is organized around method requirements, detector choice, sample introduction, carrier gas, data system, validation needs, and installed-base relevance in Iran — not only around the newest global generation.
Subcategories
Analytical GC
The Agilent 8890/8890B is a current, high-end analytical GC platform supporting up to 2 inlets, 4 detectors, dual simultaneous injection, an oven range up to 450°C, peak-area repeatability under 0.5% RSD, and retention-time repeatability under 0.008%. The Agilent 8850 is the compact option, and the Thermo Scientific TRACE 1600/1610 is a current alternate-brand reference.
GC-MS
The Agilent 5977C GC/MSD is a current single-quadrupole system for routine identification and quantitation in pharmaceutical, environmental, and food applications, covering a mass range of m/z 0.6–1091 and compatible with current Agilent GC platforms (8890, 8850, 8860, Intuvo 9000). MassHunter and OpenLab CDS software are supported.
Headspace GC
Headspace sampling is especially important for volatile compounds; its strongest pharmaceutical use case is residual-solvent testing per USP <467> and ICH Q3C. The Agilent 8697 Headspace Sampler is a current sampler with 48-vial capacity (120 with the XL tray), compatibility with 10/20/22 mL vials, and thermal control up to 300°C, offered in a reference configuration with the Agilent 8890 GC for residual-solvent analysis.
Applications
- Residual-solvent testing in raw materials and pharmaceutical products
- Identification and measurement of volatile and semi-volatile compounds
- QC of raw materials, excipients, and finished products
- Compound identification with GC-MS